MIRA Trial Results

On July 13, 2007 the MIRA (Methods for Improving Reproductive Health in Africa) diaphragm study released their findings.
The MIRA trial was designed to evaluate the ability of a latex diaphragm (used with Replens gel, a non-microbicidal lubricant) to prevent the acquisition of HIV and other sexually transmitted infections (STIs).

All MIRA trial participants received a comprehensive package of HIV prevention services including condoms, multiple condom and risk reduction counseling sessions and STI screening and treatment. In addition, women in the diaphragm arm of the trial received a diaphragm and Replens lubricant. They were asked to use these (in addition to the condom, if possible) each time they had intercourse.

In the context of this overall HIV prevention package, it was found that there was no added protective benefit from the diaphragm and lubricant and it is NOT recommended that a diaphragm be used or promoted for HIV prevention.

Below are a number statements and news stories about the MIRA results as well as tools to help advocates understand the trial results and the possible implications they may have. Please check back periodically as we will continue to update this page as more information becomes available.